From cellular microbiology to bacteria-based next generations of cancer immunotherapies.

Pioneer work by Prof. Cossart among others, studying the interactions between pathogenic bacteria and host cells (this discipline was termed Cellular Microbiology), was fundamental to determine the bacterial infection processes and to improve our knowledge of different cellular mechanisms.

The study of bacteria-host interactions also involves in vivo host immune responses, which can be manipulated by bacteria, being these last potent tools for different immunotherapies.

During the last years, tumour immunotherapies, mainly the use of antibodies that target immune checkpoints [checkpoint inhibitors (CPI)], have been a revolution in oncology, allowing the treatment of tumours otherwise with very bad prognosis. In the same direction, bacteria inoculations have been used from long to treat some cancers; for example, non-muscle-invasive bladder cancer can be successfully treated with the bacterium Bacillus Calmette Guerin (BCG).

AKR/12B-2
ABC-TC205S 1 vial Ask for price
Description: Tissue: thymus; Transformed by: X-rays. The cells express Lyt-2, Lyt-3 and CD4 in the cytosol, but not on the membrane; They reexpress Lyt-2, Lyt-3 and CD4 on the membrane after sorting by magnetic particles (5 cycles).

AKR/12B-3
ABC-TC206S 1 vial Ask for price
Description: Tissue: thymus; Transformed by: X-rays. The cells express Lyt-2, Lyt-3 and CD4 in the cytosol, but not on the membrane; They do not reexpress Lyt-2, Lyt-3 and CD4 on the membrane after sorting by magnetic particles (5 cycles).

Ala-Lys-Arg (AKR)
070-06 5 mg
EUR 102.6

Recombinant Chicken Homeobox protein AKR
MBS1464784-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1150

Recombinant Chicken Homeobox protein AKR
MBS1464784-002mgEColi 0.02mg(E-Coli)
EUR 785

Recombinant Chicken Homeobox protein AKR
MBS1464784-002mgYeast 0.02mg(Yeast)
EUR 940

Recombinant Chicken Homeobox protein AKR
MBS1464784-01mgEColi 0.1mg(E-Coli)
EUR 940

Recombinant Chicken Homeobox protein AKR
MBS1464784-01mgYeast 0.1mg(Yeast)
EUR 1100

Recombinant Neurospora crassa Palmitoyltransferase AKR1 (akr-1)
MBS7007634-002mg 0.02mg
EUR 2125

Recombinant Neurospora crassa Palmitoyltransferase AKR1 (akr-1)
MBS7007634-01mg 0.1mg
EUR 3050

Recombinant Neurospora crassa Palmitoyltransferase AKR1 (akr-1)
MBS7007634-5x01mg 5x0.1mg
EUR 13680

Recombinant Neurospora crassa Palmitoyltransferase AKR1 (akr-1), partial
MBS7087629-INQUIRE INQUIRE Ask for price

Mouse Esophageal Cancer Cell Line-AKR
CC7F9 1x 10^6 Cells/Vial Ask for price

Rabbit anti-AKV murine leukemia virus (AKR (endogenous) murine leukemia virus) POL Polyclonal Antibody
MBS7161921-INQUIRE INQUIRE Ask for price

Rabbit anti-AKV murine leukemia virus (AKR (endogenous) murine leukemia virus) env Polyclonal Antibody
MBS7161930-INQUIRE INQUIRE Ask for price

Rabbit anti-AKV murine leukemia virus (AKR (endogenous) murine leukemia virus) GAG Polyclonal Antibody
MBS7166574-INQUIRE INQUIRE Ask for price

Mouse Esophageal Cancer Cell Line-AKR-GFP-Puro
CC9F71 1x 10^6 Cells/Vial Ask for price

GIBH-130
555149 10.0mg
EUR 150

MSX-130
555221 10.0mg
EUR 150

AT-130
530587 5.0mg
EUR 350

AH-130
ABC-TC0040 1 vial Ask for price
Description: Established in vitro from the AH-130 tumor-ascites, RAP-Test negative The species was confirmed by Real-Time PCR.

GIBH-130
B2071-25 each
EUR 907.2

GIBH-130
B2071-5 each
EUR 274.8

HA 130
B1192-25 each
EUR 496.8

HA 130
B7612-10 10 mg
EUR 109.6
Description: Others|Autotaxin

HA 130
B7612-100 100mg
EUR 992
Description: Others|Autotaxin

HA 130
B7612-25 25 mg
EUR 289.2

HA 130
B7612-5 5 mg
EUR 132.8
Description: Others|Autotaxin

HA 130
B7612-50 50mg
EUR 328.8
Description: Others|Autotaxin

HA-130
MBS130680-100mg 100mg
EUR 1065

HA-130
MBS130680-500mg 500mg
EUR 2775

AT-130
HY-100028 10 mg
EUR 1136.38
Description: AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells[1][2][3].

GIBH-130
HY-101860 10mM/1mL
EUR 746.76
Description: GIBH-130 is an effective inhibitor of neuroinflammation. GIBH-130 significantly suppresses the IL-1β secretion by activated microglia (IC50=3.4 nM).

MSX-130
HY-103010 1 mg
EUR 725.12
Description: MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].

CAL-130
HY-16122A 5mg
EUR 424.8
Description: CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively.

HA-130
MBS3600904-10mg 10mg
EUR 270

HA-130
MBS3600904-25mg 25mg
EUR 350

HA-130
MBS3600904-2mg 2mg
EUR 200

HA-130
MBS3600904-50mg 50mg
EUR 480

HA-130
MBS3600904-5mg 5mg
EUR 240

GIBH-130
MBS3601012-10mg 10mg
EUR 340

GIBH-130
MBS3601012-25mg 25mg
EUR 475

GIBH-130
MBS3601012-2mg 2mg
EUR 230

GIBH-130
MBS3601012-50mg 50mg
EUR 730

GIBH-130
MBS3601012-5mg 5mg
EUR 275

CAL-130
MBS3840786-10mg 10mg
EUR 405

CAL-130
MBS3840786-50mg 50mg
EUR 925

CAL-130
MBS3840786-5mg 5mg
EUR 310

CAL-130
MBS3840786-5x50mg 5x50mg
EUR 4160

MSX-130
MBS3607496-10mg 10mg
EUR 380

MSX-130
MBS3607496-25mg 25mg
EUR 575

MSX-130
MBS3607496-2mg 2mg
EUR 285

MSX-130
MBS3607496-50mg 50mg
EUR 730

MSX-130
MBS3607496-5mg 5mg
EUR 325

GIBH-130
MBS3842799-10mg 10mg
EUR 345

GIBH-130
MBS3842799-2mg 2mg
EUR 180

GIBH-130
MBS3842799-50mg 50mg
EUR 985

GIBH-130
MBS3842799-5mg 5mg
EUR 245

GIBH-130
MBS3842799-5x50mg 5x50mg
EUR 4420

MSX-130
MBS3842125-100mg 100mg
EUR 1765

MSX-130
MBS3842125-10mg 10mg
EUR 290

MSX-130
MBS3842125-50mg 50mg
EUR 960

MSX-130
MBS3842125-5mg 5mg
EUR 210

MSX-130
MBS3842125-5x100mg 5x100mg
EUR 7940

GIBH-130
MBS5750563-10mg 10mg
EUR 225

GIBH-130
MBS5750563-25mg 25mg
EUR 370

GIBH-130
MBS5750563-2mg 2mg
EUR 155

GIBH-130
MBS5750563-50mg 50mg
EUR 560

GIBH-130
MBS5750563-5mg 5mg
EUR 175

AT-130
MBS5764862-10mg 10mg
EUR 395

AT-130
MBS5764862-1mg 1mg
EUR 175

AT-130
MBS5764862-25mg 25mg
EUR 565

AT-130
MBS5764862-50mg 50mg
EUR 810

AT-130
MBS5764862-5mg 5mg
EUR 245

CAL-130
MBS5766259-5mg 5mg
EUR 915

CAL-130
MBS5766259-5x5mg 5x5mg
EUR 3970

MSX-130
MBS579938-10mg 10mg
EUR 240

MSX-130
MBS579938-1mg 1mg
EUR 150

MSX-130
MBS579938-25mg 25mg
EUR 380

MSX-130
MBS579938-2mg 2mg
EUR 175

MSX-130
MBS579938-5mg 5mg
EUR 190

PK 130
MBS5783607-5mg 5(mg
EUR 915

PK 130
MBS5783607-5x5mg 5x5(mg
EUR 3970

LP 130
MBS5774169-5mg 5(mg
EUR 915

LP 130
MBS5774169-5x5mg 5x5(mg
EUR 3970

G-130
MBS5777105-5mg 5(mg
EUR 915

G-130
MBS5777105-5x5mg 5x5(mg
EUR 3970

PK 130
T34083-10mg 10mg Ask for price
Description: PK 130

PK 130
T34083-1g 1g Ask for price
Description: PK 130

PK 130
T34083-1mg 1mg Ask for price
Description: PK 130

PK 130
T34083-50mg 50mg Ask for price
Description: PK 130

PK 130
T34083-5mg 5mg Ask for price
Description: PK 130

AT-130
T26674-10mg 10mg Ask for price
Description: AT-130

AT-130
T26674-1g 1g Ask for price
Description: AT-130

AT-130
T26674-1mg 1mg Ask for price
Description: AT-130

AT-130
T26674-50mg 50mg Ask for price
Description: AT-130

AT-130
T26674-5mg 5mg Ask for price
Description: AT-130

G-130
T27396-10mg 10mg Ask for price
Description: G-130

G-130
T27396-1g 1g Ask for price
Description: G-130

G-130
T27396-1mg 1mg Ask for price
Description: G-130

G-130
T27396-50mg 50mg Ask for price
Description: G-130

G-130
T27396-5mg 5mg Ask for price
Description: G-130

LP 130
T24416-10mg 10mg Ask for price
Description: LP 130

LP 130
T24416-1g 1g Ask for price
Description: LP 130

LP 130
T24416-1mg 1mg Ask for price
Description: LP 130

LP 130
T24416-50mg 50mg Ask for price
Description: LP 130

LP 130
T24416-5mg 5mg Ask for price
Description: LP 130

CAL-130
T10660-10mg 10mg Ask for price
Description: CAL-130

CAL-130
T10660-1g 1g Ask for price
Description: CAL-130

CAL-130
T10660-1mg 1mg Ask for price
Description: CAL-130

CAL-130
T10660-50mg 50mg Ask for price
Description: CAL-130

CAL-130
T10660-5mg 5mg Ask for price
Description: CAL-130

MSX-130
T4033-10mg 10mg Ask for price
Description: MSX-130

MSX-130
T4033-1g 1g Ask for price
Description: MSX-130

MSX-130
T4033-1mg 1mg Ask for price
Description: MSX-130

MSX-130
T4033-50mg 50mg Ask for price
Description: MSX-130

MSX-130
T4033-5mg 5mg Ask for price
Description: MSX-130

GIBH-130
T4450-10mg 10mg Ask for price
Description: GIBH-130

GIBH-130
T4450-1g 1g Ask for price
Description: GIBH-130

GIBH-130
T4450-1mg 1mg Ask for price
Description: GIBH-130

GIBH-130
T4450-50mg 50mg Ask for price
Description: GIBH-130

GIBH-130
T4450-5mg 5mg Ask for price
Description: GIBH-130

Lenti ORF particles, AKR1C3 (Myc-DDK tagged) - Human aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR
RC200210L1V 200 µl Ask for price

Lenti ORF particles, AKR1C3 (Myc-DDK tagged) - Human aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR
RC200210L3V 200 µl Ask for price

STF 210-130*130-B7527 AC Signs
222596 Card of 1 Pictogram(s)
EUR 6.54
Description: Description Dutch: Pictogram voor Brandbestrijding - ARRÊT D'URGENCE; Description French: Pictogramme sécurité incendie - Arrêt d’urgence

STF 211-130*130-B7527 AC Signs
222598 Card of 1 Pictogram(s)
EUR 6.54
Description: Description Dutch: Pictogram voor Brandbestrijding - CLES CABINE; Description French: Pictogramme sécurité incendie - Clés cabine

STF 212-130*130-B7527 AC Signs
222600 Card of 1 Pictogram(s)
EUR 6.54
Description: Description Dutch: Pictogram voor Brandbestrijding - COUPURE D'URGENCE; Description French: Pictogramme sécurité incendie - Coupure d’urgence

STF 210-130*130-B7541 AC Signs
222832 Card of 1 Pictogram(s)
EUR 3.24
Description: Description Dutch: Pictogram voor Brandbestrijding - ARRÊT D'URGENCE; Description French: Pictogramme sécurité incendie - Arrêt d’urgence

STF 211-130*130-B7541 AC Signs
222833 Card of 1 Pictogram(s)
EUR 3.24
Description: Description Dutch: Pictogram voor Brandbestrijding - CLES CABINE; Description French: Pictogramme sécurité incendie - Clés cabine

STF 212-130*130-B7541 AC Signs
222834 Card of 1 Pictogram(s)
EUR 3.24
Description: Description Dutch: Pictogram voor Brandbestrijding - COUPURE D'URGENCE; Description French: Pictogramme sécurité incendie - Coupure d’urgence

Musclin (105-130) / Osteocrin (Ostn) (105-130) (Mouse)
028-67 100 μg
EUR 214.92

Musclin (80-130) / Osteocrin (Ostn) (80-130) (Mouse)
028-69 100 μg
EUR 355.32

CAL-130 Hydrochloride
A3268-10 10 mg
EUR 454.4
Description: PI3K/Akt/mTOR Signaling|PI3K

CAL-130 Hydrochloride
A3268-2 2mg
EUR 234.4
Description: PI3K/Akt/mTOR Signaling|PI3K

CAL-130 Hydrochloride
A3268-5 5 mg
EUR 352
Description: PI3K/Akt/mTOR Signaling|PI3K

CAL-130 Hydrochloride
A3268-5.1 10 mM (in 1mL DMSO)
EUR 584.4
Description: Class I phosphoinositide 3-kinase (PI3K) activate fundamental pathways controlling cell survival, metabolism, proliferation and and therefore play crucial role in cancer development.

CAL-130 Hydrochloride
A3268-50 50 mg
EUR 1226.4
Description: PI3K/Akt/mTOR Signaling|PI3K

AH-130 FN
ABC-TC0041 1 vial Ask for price
Description: Established in vitro from the AH-130 FN tumor ascites (Cell Lines Service), RAP-Test negativ The species was confirmed by Real-Time PCR.

nhr-130 Antibody
CSB-PA522706XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans nhr-130 protein

nhr-130 Antibody
CSB-PA522706XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans nhr-130 protein

IL16, (130 a.a.)
cyt-536 2µg
EUR 60
Description: Recombinant Human Interleukin-16, (130 a.a.)

Anticancer agent 130
HY-149890 Get quote Ask for price
Description: Anticancer agent 130 (compound 8d) is an anticancer agent that can significantly induce apoptosis in A549 cells[1].

Antibacterial agent 130
HY-152175 Get quote Ask for price
Description: Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1].

CAL-130 (Racemate)
HY-16122 50mg
EUR 1706.4
Description: CAL-130 Racemate is the racemate of CAL-130. CAL-130 Racemate is a PI3Kδ inhibitor.

CAL-130 (Hydrochloride)
HY-16122B 5mg
EUR 1293.31
Description: CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively.

Antitumor agent-130
HY-162128 Get quote Ask for price
Description: Antitumor agent-130 (Compound 7b) is a p300 histone acetyltransferases (HAT) inhibitor with an IC50 of 1.51 μM. Antitumor agent-130 combinates with doxorubicin (HY-15142A) can significantly inhibit tumor growth and invasion in vitro and in vivo[1].

ZXH-4-130
HY-132857 Get quote Ask for price
Description: ZXH-4-130 is a highly potent and selective degrader of CRBN. ZXH-4-130 is a CRBN-VHL compound (hetero-PROTAC)[1].

AC-4-130
HY-124500 10 mg
EUR 1406.95
Description: AC-4-130 is a potent STAT5 SH2 domain inhibitor. AC-4-130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent gene transcription. AC-4-130 induces cell cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells. AC-4-130 has anti-cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML)[1].

CAL-130 Hydrochloride
MBS3840787-10mg 10mg
EUR 405

CAL-130 Hydrochloride
MBS3840787-50mg 50mg
EUR 925

CAL-130 Hydrochloride
MBS3840787-5mg 5mg
EUR 310

CAL-130 Hydrochloride
MBS3840787-5x50mg 5x50mg
EUR 4160

CAL-130 Racemate
MBS3845378-10mg 10mg
EUR 1905

CAL-130 Racemate
MBS3845378-1mg 1mg
EUR 430

CAL-130 Racemate
MBS3845378-5mg 5mg
EUR 1165

CAL-130 Racemate
MBS3845378-5x10mg 5x10mg
EUR 8565

AC-4-130
MBS3842780-10mg 10mg
EUR 1210

AC-4-130
MBS3842780-50mg 50mg
EUR 4080

AC-4-130
MBS3842780-5mg 5mg
EUR 690

AC-4-130
MBS3842780-5x50mg 5x50mg
EUR 18350

CAL-130 Hydrochloride
MBS5752847-50mg 50mg
EUR 1095

CAL-130 Hydrochloride
MBS5752847-5x50mg 5x50mg
EUR 4785

AC-4-130
MBS5784895-10mg 10mg
EUR 375

AC-4-130
MBS5784895-25mg 25mg
EUR 675

AC-4-130
MBS5784895-50mg 50mg
EUR 1515

AC-4-130
MBS5784895-5mg 5(mg
EUR 280

ZXH-4-130
MBS5800596-5mg 5(mg
EUR 915

ZXH-4-130
MBS5800596-5x5mg 5x5(mg
EUR 3970

CAL-130 Racemate
MBS5789795-5mg 5(mg
EUR 915

CAL-130 Racemate
MBS5789795-5x5mg 5x5(mg
EUR 3970

AC-4-130
T35429-10mg 10mg Ask for price
Description: AC-4-130

AC-4-130
T35429-1g 1g Ask for price
Description: AC-4-130

AC-4-130
T35429-1mg 1mg Ask for price
Description: AC-4-130

AC-4-130
T35429-50mg 50mg Ask for price
Description: AC-4-130

AC-4-130
T35429-5mg 5mg Ask for price
Description: AC-4-130

CAL-130 Hydrochloride
T10660L-10mg 10mg Ask for price
Description: CAL-130 Hydrochloride

CAL-130 Hydrochloride
T10660L-1g 1g Ask for price
Description: CAL-130 Hydrochloride

CAL-130 Hydrochloride
T10660L-1mg 1mg Ask for price
Description: CAL-130 Hydrochloride

CAL-130 Hydrochloride
T10660L-50mg 50mg Ask for price
Description: CAL-130 Hydrochloride

CAL-130 Hydrochloride
T10660L-5mg 5mg Ask for price
Description: CAL-130 Hydrochloride

CAL-130 Racemate
T10660L2-10mg 10mg Ask for price
Description: CAL-130 Racemate

CAL-130 Racemate
T10660L2-1g 1g Ask for price
Description: CAL-130 Racemate

CAL-130 Racemate
T10660L2-1mg 1mg Ask for price
Description: CAL-130 Racemate

CAL-130 Racemate
T10660L2-50mg 50mg Ask for price
Description: CAL-130 Racemate

CAL-130 Racemate
T10660L2-5mg 5mg Ask for price
Description: CAL-130 Racemate

ZXH-4-130
T40332-10mg 10mg Ask for price
Description: ZXH-4-130

ZXH-4-130
T40332-1g 1g Ask for price
Description: ZXH-4-130

ZXH-4-130
T40332-1mg 1mg Ask for price
Description: ZXH-4-130

ZXH-4-130
T40332-50mg 50mg Ask for price
Description: ZXH-4-130

ZXH-4-130
T40332-5mg 5mg Ask for price
Description: ZXH-4-130